Aloe Vera
Overview
Aloe vera (Aloe barbadensis Miller) contains two distinct components with different pharmacology: (1) Inner gel (acemannan polysaccharides, C2H3O·n) supports mucosal integrity, wound healing, and immune modulation — limited RCT evidence for IBD and glycemic control. (2) Latex (outer leaf; anthraquinone glycosides: aloin, barbaloin) acts as a potent laxative via stimulation of prostaglandin E2 and water secretion into colon. CRITICAL INTERACTIONS: Latex fraction: risk of electrolyte depletion (hypokalemia) potentiates cardiac glycosides (digoxin) toxicity — avoid combination; additive potassium-depleting effect with loop/thiazide diuretics; may enhance hypoglycemic effect of antidiabetics. Gel fraction: generally safe topically and orally in moderation. Latex use >10 days not recommended; potential hepatotoxicity at high oral doses.
Dosage
100 mg · With meal · Take with food
Scientific Sources
Frequently Asked Questions
What is Aloe Vera used for?
Aloe vera (Aloe barbadensis Miller) contains two distinct components with different pharmacology: (1) Inner gel (acemannan polysaccharides, C2H3O·n) supports mucosal integrity, wound healing, and immune modulation — limited RCT evidence for IBD and glycemic control.
What is the recommended dosage for Aloe Vera?
100 mg. With meal. Take with food.
Does Aloe Vera interact with other supplements?
No verified interactions found for Aloe Vera in our database yet.
When is the best time to take Aloe Vera?
With meal. Take with food.
Is Aloe Vera safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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