Traubensilberkerze (Cimicifuga racemosa)
Overview
Black cohosh (Actaea racemosa) root extract contains cycloartanol triterpene glycosides (actein, C37H56O10) and phenolic acids. Mechanism: SERM-like activity via serotonin 5-HT1A/5-HT7 receptors — not direct estrogenic agonism. Used for menopausal vasomotor symptoms (hot flashes, night sweats). A 2025 systematic review of 14 trials found variable study quality; further high-quality research needed. Rare hepatotoxicity cases reported — monitor liver enzymes with long-term use. Caution with hormone-sensitive cancers (precautionary). CYP2D6 inhibitor — may affect tamoxifen metabolism. Contraindicated in pregnancy.
Dosage
40 mg · Any time · Can take on empty stomach
Frequently Asked Questions
What is Traubensilberkerze (Cimicifuga racemosa) used for?
Black cohosh (Actaea racemosa) root extract contains cycloartanol triterpene glycosides (actein, C37H56O10) and phenolic acids.
What is the recommended dosage for Traubensilberkerze (Cimicifuga racemosa)?
40 mg. Any time. Can take on empty stomach.
Does Traubensilberkerze (Cimicifuga racemosa) interact with other supplements?
No verified interactions found for Traubensilberkerze (Cimicifuga racemosa) in our database yet.
When is the best time to take Traubensilberkerze (Cimicifuga racemosa)?
Any time. Can take on empty stomach.
Is Traubensilberkerze (Cimicifuga racemosa) safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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