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Artischocke (Cynara scolymus)

Herb Evidence: moderate

Overview

Artichoke (Cynara scolymus) extract contains cynarin, luteolin, and chlorogenic acid, acting as a bile stimulant, cholesterol-lowering agent, and hepatoprotective. A 2025 systematic review and meta-analysis confirmed significant reductions in BMI, blood pressure, total cholesterol, LDL, triglycerides, and liver enzymes. No significant effect on HDL; renal safety confirmed. Contraindicated in bile duct obstruction and gallstones. Cross-reactivity possible in Asteraceae-allergic individuals.

Dosage

500 mg · With meal · Take with food

Key Interactions

1 verified interaction found

Milk Thistle protects hepatocytes; Artichoke (Cynarin) stimulates bile production and supports cholesterol metabolism. Complementary liver and digestive support.

Combine for liver and bile health.

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Scientific Sources

Frequently Asked Questions

What is Artischocke (Cynara scolymus) used for?

Artichoke (Cynara scolymus) extract contains cynarin, luteolin, and chlorogenic acid, acting as a bile stimulant, cholesterol-lowering agent, and hepatoprotective.

What is the recommended dosage for Artischocke (Cynara scolymus)?

500 mg. With meal. Take with food.

Does Artischocke (Cynara scolymus) interact with other supplements?

Artischocke (Cynara scolymus) has 1 verified interactions. Top: Milk Thistle (Mariendistel).

When is the best time to take Artischocke (Cynara scolymus)?

With meal. Take with food.

Is Artischocke (Cynara scolymus) safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.