Glucuronolactone
Overview
D-Glucuronolactone (C6H8O6, CID 92283) is an endogenous lactone derivative of glucuronic acid, formed in the liver via glucose metabolism through the uronic acid pathway. Present in energy drinks (Red Bull: 600 mg/can) alongside caffeine and taurine; marketed as ergogenic agent for mental alertness and detoxification support. Mechanisms in humans are poorly established. Small controlled trials with energy drink formulations show modest improvements in cognitive performance and reaction time, though these are likely attributable primarily to caffeine. Insufficient standalone clinical evidence. No established toxicity at 600–1000 mg supplemental doses. INTERACTIONS: potential weak interaction with anticoagulants via glucuronidation pathway; no major drug interactions documented. Insufficient data for strong safety conclusions at very high doses.
Dosage
600 mg · Morning · Take with food
Scientific Sources
Frequently Asked Questions
What is Glucuronolactone used for?
D-Glucuronolactone (C6H8O6, CID 92283) is an endogenous lactone derivative of glucuronic acid, formed in the liver via glucose metabolism through the uronic acid pathway.
What is the recommended dosage for Glucuronolactone?
600 mg. Morning. Take with food.
Does Glucuronolactone interact with other supplements?
No verified interactions found for Glucuronolactone in our database yet.
When is the best time to take Glucuronolactone?
Morning. Take with food.
Is Glucuronolactone safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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