Teufelskralle (Harpagophytum procumbens)
Overview
Devil's claw (Harpagophytum procumbens) contains harpagoside (C24H30O11) as the primary anti-inflammatory iridoid glycoside, inhibiting COX-1/COX-2, 5-LOX, and TNF-α. A Cochrane review of 12 RCTs found harpagoside (50–100 mg/day) more effective than placebo for non-specific low back pain; comparable to rofecoxib at moderate doses (moderate evidence quality). Generally well tolerated. Contraindicated in peptic ulcer disease. Antiplatelet activity — caution with anticoagulants. Contraindicated in pregnancy.
Dosage
960 mg · Any time · Can take on empty stomach
Frequently Asked Questions
What is Teufelskralle (Harpagophytum procumbens) used for?
Devil's claw (Harpagophytum procumbens) contains harpagoside (C24H30O11) as the primary anti-inflammatory iridoid glycoside, inhibiting COX-1/COX-2, 5-LOX, and TNF-α.
What is the recommended dosage for Teufelskralle (Harpagophytum procumbens)?
960 mg. Any time. Can take on empty stomach.
Does Teufelskralle (Harpagophytum procumbens) interact with other supplements?
No verified interactions found for Teufelskralle (Harpagophytum procumbens) in our database yet.
When is the best time to take Teufelskralle (Harpagophytum procumbens)?
Any time. Can take on empty stomach.
Is Teufelskralle (Harpagophytum procumbens) safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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