Selank

Peptide Evidence: strong

Overview

Selank is a synthetic heptapeptide anxiolytic derived from tuftsin (Thr-Lys-Pro-Arg), developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It modulates GABA-A receptor activity, increases BDNF expression, and influences serotonin and enkephalin systems. Published Russian clinical trials have used intranasal doses in the range of 250–500 mcg. Studied for anxiety reduction and cognitive enhancement without sedation or dependence. Evidence is primarily from Russian research institutions; limited independent replication in Western peer-reviewed literature. Consult a licensed physician before use.

Dosage

250 mcg · Any time · Can take on empty stomach

Key Interactions

1 verified interaction found

Baldrian-Extrakt Caution

Selank modulates GABA-A receptor activity and influences serotonergic pathways. Valerian (Baldrian) also potentiates GABAergic transmission. Combining GABAergic compounds may produce additive CNS-depressant effects including increased sedation and impaired cognitive performance.

Combining Selank with other GABAergic supplements (Valerian, Passionflower, GABA, Lemon Balm) may produce additive sedation. Exercise caution regarding activities requiring alertness. Consult a physician.

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Scientific Sources

Frequently Asked Questions

What is Selank used for?

Selank is a synthetic heptapeptide anxiolytic derived from tuftsin (Thr-Lys-Pro-Arg), developed by the Institute of Molecular Genetics of the Russian Academy of Sciences.

What is the recommended dosage for Selank?

250 mcg. Any time. Can take on empty stomach.

Does Selank interact with other supplements?

Selank has 1 verified interactions. Top: Baldrian-Extrakt.

When is the best time to take Selank?

Any time. Can take on empty stomach.

Is Selank safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.