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Semax

Peptide Evidence: strong

Overview

Semax is a synthetic heptapeptide based on the ACTH(4-7) sequence (Met-Glu-His-Phe) with a Pro-Gly-Pro C-terminal extension to improve stability. Developed in Russia, it upregulates BDNF and NGF, modulates dopaminergic and serotonergic neurotransmission, and demonstrates neuroprotective effects in ischemia animal models. Russian clinical research has used intranasal doses in the 200–600 mcg range for cognitive and neuroprotective applications. Used clinically in Russia for stroke rehabilitation and cognitive impairment; limited independent replication outside Russian research. Consult a licensed physician before use.

Dosage

300 mcg · Any time · Can take on empty stomach

Scientific Sources

Frequently Asked Questions

What is Semax used for?

Semax is a synthetic heptapeptide based on the ACTH(4-7) sequence (Met-Glu-His-Phe) with a Pro-Gly-Pro C-terminal extension to improve stability.

What is the recommended dosage for Semax?

300 mcg. Any time. Can take on empty stomach.

Does Semax interact with other supplements?

No verified interactions found for Semax in our database yet.

When is the best time to take Semax?

Any time. Can take on empty stomach.

Is Semax safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.