Alpha-Linolenic Acid (ALA)
Overview
Alpha-Linolenic Acid (ALA, C18:3n-3, C18H30O2, CID 5280934) is an essential plant-derived omega-3 fatty acid found abundantly in flaxseed (55%), chia seeds (60%), walnuts (13%), and canola oil. Serves as biochemical precursor for EPA and DHA, but human enzymatic conversion is highly inefficient (5–10% to EPA; <1% to DHA). Strong epidemiological and prospective cohort evidence supports inverse association with cardiovascular mortality; multiple RCTs demonstrate anti-inflammatory effects via prostaglandin pathway modulation. NOTE: "ALA" is a shared abbreviation — Alpha-Linolenic Acid (omega-3) is entirely distinct from Alpha-Lipoic Acid (antioxidant). INTERACTIONS: additive anticoagulant/antiplatelet effects with warfarin, aspirin, and other blood thinners — monitor INR; may reduce absorption of fat-soluble medications. Generally safe at 1.5–3 g/day.
Dosage
2000 mg · With meal · Take with food
Scientific Sources
Frequently Asked Questions
What is Alpha-Linolenic Acid (ALA) used for?
Alpha-Linolenic Acid (ALA, C18:3n-3, C18H30O2, CID 5280934) is an essential plant-derived omega-3 fatty acid found abundantly in flaxseed (55%), chia seeds (60%), walnuts (13%), and canola oil.
What is the recommended dosage for Alpha-Linolenic Acid (ALA)?
2000 mg. With meal. Take with food.
Does Alpha-Linolenic Acid (ALA) interact with other supplements?
No verified interactions found for Alpha-Linolenic Acid (ALA) in our database yet.
When is the best time to take Alpha-Linolenic Acid (ALA)?
With meal. Take with food.
Is Alpha-Linolenic Acid (ALA) safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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