Apigenin
Overview
Apigenin is a flavonoid found in chamomile that acts as a partial agonist at GABA-A receptors and inhibits the enzyme CD38 (a key NAD+ consumer). At 50 mg taken before sleep it is used as a mild anxiolytic and sleep aid.
Dosage
50 mg · Evening · Can take on empty stomach
What Experts Say
“there are supplements that for most people will greatly improve their ability to fall and stay asleep and the three main supplements in that category are magnesium threonate, apigenin, and theanine... 50 milligrams of apigenin”
Huberman includes 50 mg apigenin as one of three core sleep supplements (with magnesium threonate and theanine), noting it works via GABA and chloride channel pathways. He has taken it nightly for over 8 years and describes it as one of the most reliably beneficial sleep aids in his protocol.
Scientific Sources
Frequently Asked Questions
What is Apigenin used for?
Apigenin is a flavonoid found in chamomile that acts as a partial agonist at GABA-A receptors and inhibits the enzyme CD38 (a key NAD+ consumer).
What is the recommended dosage for Apigenin?
50 mg. Evening. Can take on empty stomach.
Does Apigenin interact with other supplements?
No verified interactions found for Apigenin in our database yet.
When is the best time to take Apigenin?
Evening. Can take on empty stomach.
Is Apigenin safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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