Chamomile
Overview
Chamomile (Matricaria chamomilla / recutita) dried flower extract contains apigenin (CID 5280443), bisabolol, and flavonoids that bind GABA-A receptors (benzodiazepine-like modulation), reducing anxiety-related neural activity and promoting sleep onset. Meta-analysis of 14 RCTs shows significant efficacy for generalized anxiety disorder (HAM-A improvement) and sleep quality (SMD=−0.73, p<0.005). Cortisol-modulating effects confirmed in controlled trials. INTERACTIONS: potentiates CNS depressants (benzodiazepines, sedatives, alcohol); weak anticoagulant potential — caution with warfarin (monitor INR); cross-reactive with ragweed allergens in sensitized individuals. Well-tolerated; rare serious adverse events documented at standard doses.
Dosage
300 mg · Evening · Can take on empty stomach
Scientific Sources
Frequently Asked Questions
What is Chamomile used for?
Chamomile (Matricaria chamomilla / recutita) dried flower extract contains apigenin (CID 5280443), bisabolol, and flavonoids that bind GABA-A receptors (benzodiazepine-like modulation), reducing anxiety-related neural activity and promoting sleep onset.
What is the recommended dosage for Chamomile?
300 mg. Evening. Can take on empty stomach.
Does Chamomile interact with other supplements?
No verified interactions found for Chamomile in our database yet.
When is the best time to take Chamomile?
Evening. Can take on empty stomach.
Is Chamomile safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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