Magnesium L-Threonat
Overview
Magnesium L-threonate is magnesium bound to L-threonic acid, designed for enhanced blood-brain barrier penetration via glucose transporters. Sold as Magtein®, typical products provide 1,000–2,000 mg/day (yielding ~144 mg elemental magnesium). It is the most expensive magnesium form. Same general safety applies: supplement upper limit is 350 mg elemental magnesium per day; avoid without medical supervision in kidney disease.
Dosage
2000 mg · Evening · Take with food
Key Interactions
1 verified interaction found
Mg L-threonate primarily accumulates in brain tissue. Elemental Mg dose (108-144 mg/day effective) may not fully cover cofactor needs for D3 at high D3 doses. Consider adding a second Mg form if using >50 mcg D3/day.
Evening Mg L-Threonat + morning D3. Add Mg Glycinat or Citrat if D3 dose is high.
View details →Scientific Sources
- RCT n=100, 6w, 2g/day: NIH cognitive composite, reaction time, HRV improved
- RCT n=80, 1g/day 21d: deep/REM sleep, mood, alertness improved
- RCT n=109, 2g/day: all 5 CMT memory subcategories improved
- Effective elemental dose 108-144mg/day within safe limits
- Compound: Magnesium-L-threonate
- pubmed_ncbi_api
- pubmed_ncbi_api
- Elemental dose 108-144mg, brain-selective
- Mg cofactor for D3 activation
- PubChem Compound 71307398
Frequently Asked Questions
What is Magnesium L-Threonat used for?
Magnesium L-threonate is magnesium bound to L-threonic acid, designed for enhanced blood-brain barrier penetration via glucose transporters.
What is the recommended dosage for Magnesium L-Threonat?
2000 mg. Evening. Take with food.
Does Magnesium L-Threonat interact with other supplements?
Magnesium L-Threonat has 1 verified interactions. Top: Vitamin D3 (Cholecalciferol).
When is the best time to take Magnesium L-Threonat?
Evening. Take with food.
Is Magnesium L-Threonat safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
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