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Chrom

Mineral Evidence: moderate

Overview

Chromium is an essential ultratrace mineral proposed to potentiate insulin action via chromodulin. Adequate intake: 20–35 mcg/day; no upper limit established. Evidence for blood glucose lowering is contested: a 2019 meta-analysis of 58 trials found only slight effects; the American Diabetes Association does not recommend routine supplementation. FDA permits only a qualified health claim that the relationship to diabetes risk is "highly uncertain." Caution with insulin, metformin (hypoglycemia risk), and levothyroxine (reduced absorption).

Dosage

50 mcg · Any time · Can take on empty stomach

Key Interactions

3 verified interactions found

Eisen Caution

Chromium and Iron compete for transferrin binding. Co-administration may reduce absorption of both.

Separate by 3+ hours.

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Berberine Info

Both improve insulin sensitivity. Chromium enhances insulin receptor signaling; Berberine activates AMPK.

Combine for metabolic support. Monitor blood sugar if diabetic.

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Alpha-lipoic acid Info

Both improve insulin sensitivity. Chromium as signaling cofactor, ALA via GLUT4 enhancement.

Combine for blood sugar management.

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Scientific Sources

Frequently Asked Questions

What is Chrom used for?

Chromium is an essential ultratrace mineral proposed to potentiate insulin action via chromodulin.

What is the recommended dosage for Chrom?

50 mcg. Any time. Can take on empty stomach.

Does Chrom interact with other supplements?

Chrom has 3 verified interactions. Top: Eisen, Berberine.

When is the best time to take Chrom?

Any time. Can take on empty stomach.

Is Chrom safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

Check how Chrom fits your full stack

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.