← All Supplements

Kupfer

Mineral Evidence: strong

Overview

Copper is an essential trace mineral and cofactor for enzymes involved in energy production, iron metabolism (ceruloplasmin), connective tissue synthesis, and neurotransmitter function. RDA: 900 µg/day (adults); upper limit: 10,000 µg/day. Deficiency causes anemia and neurological symptoms; toxicity causes nausea and liver damage. High zinc intake (>50 mg/day) depletes copper by competing for intestinal absorption. Wilson's disease (genetic copper accumulation disorder) is a contraindication for supplementation.

Dosage

1 mg · Morning · Take with food

Key Interactions

2 verified interactions found

Zink Warning

High-dose zinc supplementation (>25-50mg/day) competitively inhibits copper absorption via metallothionein induction and DMT1 transporter competition. Chronic high zinc depletes copper stores, causing deficiency anemia, neurological symptoms, and impaired immune function

If taking >25mg zinc daily, supplement 1-2mg copper to prevent deficiency. Maintain zinc:copper ratio ~8-15:1. Monitor copper levels annually.

View details →
Zink Warning

Hochdosierte Zinkeinnahme (>40 mg/Tag über Wochen/Monate) führt zu Kupfermangel durch Metallothionein-Induktion. Klinisch dokumentierte Folgen: Ataxie, Myelopathie, Anämie, Leukopenie durch Zink-induzierten Kupfermangel.

Bei Zinkdosen >25 mg/Tag Kupferstatus beobachten (Serum-Kupfer, Coeruloplasmin). Bei Langzeit-Hochdosierung (>40 mg/Tag) prophylaktische Kupfer-Supplementierung (Verhältnis ~10:1 Zink:Kupfer). Kupfer und Zink zeitversetzt einnehmen.

View details →

Scientific Sources

Frequently Asked Questions

What is Kupfer used for?

Copper is an essential trace mineral and cofactor for enzymes involved in energy production, iron metabolism (ceruloplasmin), connective tissue synthesis, and neurotransmitter function.

What is the recommended dosage for Kupfer?

1 mg. Morning. Take with food.

Does Kupfer interact with other supplements?

Kupfer has 2 verified interactions. Top: Zink, Zink.

When is the best time to take Kupfer?

Morning. Take with food.

Is Kupfer safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

Check how Kupfer fits your full stack

Verify interactions, get timing plans, and optimize your supplement routine — free.

Check Your Stack →

Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.