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DHEA (Dehydroepiandrosteron)

Hormone Evidence: moderate

Overview

DHEA (dehydroepiandrosterone, C19H28O2) is an adrenal steroid that declines with age, converted to estrogens and testosterone. Intravaginal prasterone (Intrarosa®) has regulatory approval for vaginal atrophy. Critical safety concerns: DHEA promotes growth in hormone-sensitive cancers (breast, prostate, endometrial). Androgenic side effects possible in women. Interactions with hormone therapies. Banned by WADA in competitive sports. Requires prescription in Germany; laboratory monitoring of hormone levels recommended.

Dosage

25 mg · Morning · Can take on empty stomach

Key Interactions

3 verified interactions found

Pregnenolon Caution

Both are adrenal hormone precursors competing for enzymatic conversion; may create hormonal imbalance if combined

Do not combine DHEA with Pregnenolone; if using either, ensure adequate monitoring of hormone levels

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Vitamin D3 (Cholecalciferol) Info

DHEA is a precursor for sex hormones; Vitamin D3 supports hormonal balance via VDR signaling. Both decline with age and support overall hormonal health.

Combine under medical supervision. Monitor hormone levels.

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Zink Info

DHEA converts to androgens; Zinc supports the enzymatic conversion via aromatase modulation.

Combine for hormonal support. Medical supervision recommended.

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Scientific Sources

Frequently Asked Questions

What is DHEA (Dehydroepiandrosteron) used for?

DHEA (dehydroepiandrosterone, C19H28O2) is an adrenal steroid that declines with age, converted to estrogens and testosterone.

What is the recommended dosage for DHEA (Dehydroepiandrosteron)?

25 mg. Morning. Can take on empty stomach.

Does DHEA (Dehydroepiandrosteron) interact with other supplements?

DHEA (Dehydroepiandrosteron) has 3 verified interactions. Top: Pregnenolon, Vitamin D3 (Cholecalciferol).

When is the best time to take DHEA (Dehydroepiandrosteron)?

Morning. Can take on empty stomach.

Is DHEA (Dehydroepiandrosteron) safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

Check how DHEA (Dehydroepiandrosteron) fits your full stack

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.