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Zeaxanthin

Antioxidant Evidence: moderate

Overview

Zeaxanthin (C40H56O2) is a xanthophyll carotenoid that concentrates in the central fovea of the macula lutea and functions as a selective blue-light absorber (400–500 nm) and free-radical quencher. Clinical evidence from AREDS2 and multiple RCTs supports 2–10 mg daily (combined with lutein) for reducing progression to advanced age-related macular degeneration. Almost always sold paired with Lutein — both compete for the same carotenoid transport pathway; combined supplementation is preferred. Fat-soluble: requires dietary fat for absorption. No significant drug interactions; excellent safety profile at supplemental doses.

Dosage

10 mg · With meal · Take with food

Key Interactions

1 verified interaction found

Lutein Info

Both are carotenoids concentrated in retina; complementary antioxidant and photoprotective effects

Should be combined for optimal eye health; both necessary for macular pigment optical density

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Scientific Sources

Frequently Asked Questions

What is Zeaxanthin used for?

Zeaxanthin (C40H56O2) is a xanthophyll carotenoid that concentrates in the central fovea of the macula lutea and functions as a selective blue-light absorber (400–500 nm) and free-radical quencher.

What is the recommended dosage for Zeaxanthin?

10 mg. With meal. Take with food.

Does Zeaxanthin interact with other supplements?

Zeaxanthin has 1 verified interactions. Top: Lutein.

When is the best time to take Zeaxanthin?

With meal. Take with food.

Is Zeaxanthin safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.