Lutein
Overview
Lutein (C40H56O2) is a xanthophyll carotenoid concentrated in the macula alongside zeaxanthin, forming macular pigment that filters blue light. An umbrella review of 25 meta-analyses found suggestive evidence for reduced cataract risk and AMD risk reduction. AREDS2 supports lutein+zeaxanthin (10 mg + 2 mg/day) replacing beta-carotene for AMD supplementation. Fat-soluble — take with a fatty meal. Generally well tolerated; no established upper limit. In smokers, prefer lutein over beta-carotene.
Dosage
10 mg · Any time · Can take on empty stomach
Key Interactions
7 verified interactions found
Hohe Beta-Carotin-Dosen können die Bioverfügbarkeit von Lutein verringern. Relevant für Augengesundheits-Supplementierungen, bei denen Lutein im Vordergrund steht.
Hohe Beta-Carotin-Dosen (>3mg) können die Aufnahme von Lutein reduzieren. Für optimale Lutein-Versorgung zeitversetzt einnehmen oder Gesamtdosis beider Carotinoide beachten.
View details →Lutein and retinol levels change together during dietary interventions, reflecting coordinated absorption.
Vitamin A (Retinol) und Lutein können bei hoher Dosierung um Transportproteine konkurrieren und sich gegenseitig in der Aufnahme beeinflussen. Eine zeitlich versetzte Einnahme (ca. 2 Stunden Abstand) kann eine mögliche Konkurrenzsituation reduzieren.
View details →Selenium application enhances lutein concentration in edible herbs by up to 19 percent.
Selen-Anwendung kann laut präklinischer Daten die Lutein-Konzentration erhöhen; beim Menschen ist eine vergleichbare Bioverfügbarkeitssteigerung nicht belegt. Eine gleichzeitige Einnahme ist unbedenklich.
View details →Both are carotenoids concentrated in retina; complementary antioxidant and photoprotective effects
Should be combined for optimal eye health; both necessary for macular pigment optical density
View details →Lutein protects riboflavin from light-induced degradation, keeping riboflavin stable and active during yogurt storage.
Lutein kann laut präklinischer Daten die Stabilität von Riboflavin während der Lagerung verbessern. Eine gemeinsame Einnahme ist unbedenklich.
View details →Scientific Sources
- PubChem CID:5281243
- Smoking, dietary factors and major age-related eye disorders: an umbrella review of system... (Br J Ophthalmol, 2023 Dec 18)
- pubmed_ncbi_api
- pubmed_ncbi_api
- Bioavailability of lutein from vegetables is 5 times higher than that of beta-ca (1999)
- Intestinal absorption, serum clearance, and interactions between lutein and beta (1995)
- Carotenoid interactions. (1999)
- Effect of lutein on beta-carotene absorption and cleavage. (1998)
- Investigation of beta-carotene and lutein transport in Caco-2 cells: carotenoid- (2009)
- The possible significance of parallel changes in plasma lutein and retinol in Pa (1997)
- Micronutrient concentrations in paired skin and plasma of patients with actinic (1993)
- Relative Gastro-Intestinal Stability of Carotene and Vitamin A and Protective Ef (1947)
- Selenium Biofortification Impacts the Nutritive Value, Polyphenolic Content, and (2020)
- Oxidative stability of yogurt with added lutein dye. (2014)
- NIH Dietary Supplement Label Database (DSLD)
- PubChem Compound 5281243
Frequently Asked Questions
What is Lutein used for?
Lutein (C40H56O2) is a xanthophyll carotenoid concentrated in the macula alongside zeaxanthin, forming macular pigment that filters blue light.
What is the recommended dosage for Lutein?
10 mg. Any time. Can take on empty stomach.
Does Lutein interact with other supplements?
Lutein has 7 verified interactions. Top: Beta Carotene, Vitamin A (Retinol).
When is the best time to take Lutein?
Any time. Can take on empty stomach.
Is Lutein safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
Check how Lutein fits your full stack
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Check Your Stack →Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.