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Molybdenum

Mineral Evidence: strong

Overview

Molybdenum (Mo, atomic number 42) is an essential trace mineral functioning as cofactor for four critical enzymes: sulfite oxidase, xanthine oxidase, aldehyde oxidase, and mitochondrial amidoxime-reducing component (MARC). These enzymes are essential for sulfite detoxification, purine/pyrimidine catabolism, and xenobiotic metabolism. Dietary requirement met by legumes, grains, and organ meats; clinical deficiency is extremely rare (isolated cases in total parenteral nutrition). EU RDA: 50 mcg/day; Tolerable Upper Intake Level: 600 mcg/day. At physiologic supplemental doses, no known drug interactions. HIGH-DOSE CAUTION: >600 mcg/day may compete with copper absorption (monitor copper status); joint pain and hyperuricemia reported at extremely high doses (10–15 mg/day).

Dosage

45 mcg · Any time · Can take on empty stomach

Key Interactions

3 verified interactions found

Eisen Caution

Molybdenum and Iron have complex interactions in copper-iron-molybdenum metabolism. High molybdenum may affect iron utilization.

Take separately if supplementing both.

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Zink Caution

Both are trace minerals that may compete for absorption at high doses. Clinical significance is low at typical supplemental doses.

Separate by 2 hours if taking high doses.

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Eisen Info

Molybdenum not typically competing with iron for absorption

No specific separation needed from iron

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Scientific Sources

Frequently Asked Questions

What is Molybdenum used for?

Molybdenum (Mo, atomic number 42) is an essential trace mineral functioning as cofactor for four critical enzymes: sulfite oxidase, xanthine oxidase, aldehyde oxidase, and mitochondrial amidoxime-reducing component (MARC).

What is the recommended dosage for Molybdenum?

45 mcg. Any time. Can take on empty stomach.

Does Molybdenum interact with other supplements?

Molybdenum has 3 verified interactions. Top: Eisen, Zink.

When is the best time to take Molybdenum?

Any time. Can take on empty stomach.

Is Molybdenum safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.