Tribulus terrestris

Herb Evidence: limited

Overview

Tribulus terrestris contains steroidal saponins including protodioscin (C51H84O22). A meta-analysis of 8 RCTs found significant improvement in erectile function (IIEF-5: +4.21 vs. placebo) but no significant increase in testosterone levels — the claimed testosterone-boosting effect is not supported by meta-analytic evidence. Benefits for erectile dysfunction operate through non-testosterone mechanisms. Generally well tolerated. No evidence for athletic performance enhancement. Contraindicated in hormone-sensitive prostate cancer. Monitor blood glucose with antidiabetics.

Dosage

750 mg · With meal · Take with food

Key Interactions

2 verified interactions found

Maca Info

Both support hormonal health through different mechanisms. Maca modulates the hypothalamic-pituitary axis; Tribulus supports luteinizing hormone signaling.

Combine for hormonal and vitality support.

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Zink Info

Tribulus supports LH signaling; Zinc is a direct cofactor for testosterone synthesis.

Combine for male hormonal support.

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Scientific Sources

Frequently Asked Questions

What is Tribulus terrestris used for?

Tribulus terrestris contains steroidal saponins including protodioscin (C51H84O22).

What is the recommended dosage for Tribulus terrestris?

750 mg. With meal. Take with food.

Does Tribulus terrestris interact with other supplements?

Tribulus terrestris has 2 verified interactions. Top: Maca, Zink.

When is the best time to take Tribulus terrestris?

With meal. Take with food.

Is Tribulus terrestris safe to combine with other supplements?

Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.

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Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.