EPA (Omega-3)
Overview
EPA (eicosapentaenoic acid) is an omega-3 fatty acid involved in producing eicosanoids — signaling molecules with anti-inflammatory properties. Found in fatty fish and fish oil supplements. Relevant for cardiovascular and immune function. Up to 3 g/day combined EPA+DHA is considered safe. Higher doses may increase bleeding time; use caution with anticoagulants. Often supplemented together with DHA.
Dosage
1200 mg · With meal · Take with food
Key Interactions
10 verified interactions found
Schwarzkümmelöl enthält ~55% Linolsäure (Omega-6). Diese konkurriert mit EPA um Delta-5/Delta-6-Desaturasen und um Phospholipid-Einbau in Zellmembranen. Dadurch kann die anti-inflammatorische Wirkung von EPA abgeschwächt werden.
Schwarzkümmelöl und EPA-Supplementierung nicht gleichzeitig hochdosiert einnehmen. Bei Kombination: BSO-Dosis begrenzen (≤2 ml/Tag), EPA-Zufuhr erhöhen. Ziel: Omega-6:Omega-3-Ratio ≤ 4:1.
View details →EPA reduces prostaglandins; Boswellia inhibits 5-LOX leukotrienes. Dual inflammatory pathway targeting.
Combine for joint and inflammatory support.
View details →CoQ10 protects EPA from peroxidation. Both support cardiovascular health from antioxidant and lipid angles.
Combine for heart health.
View details →Vitamin C protects EPA from oxidative degradation. Both support cardiovascular and immune health.
Combine freely.
View details →EPA modulates inflammation; Zinc supports immune cells. Both support immune balance.
Combine for immune health.
View details →Scientific Sources
- Source
- Source
- EPA omega-3 + Boswellia combination study (PMID:39937638)
- EPA omega-3 + Boswellia combination study (PMID:39201362)
- EPA omega-3 + Boswellia combination study (PMID:37028557)
- EPA omega-3 + CoQ10 combination study (PMID:30813440)
- EPA omega-3 + CoQ10 combination study (PMID:23297818)
- EPA omega-3 + CoQ10 combination study (PMID:25141367)
- EPA omega-3 + Vitamin C combination study (PMID:24685324)
- EPA omega-3 + Vitamin C combination study (PMID:12837515)
- EPA omega-3 + Vitamin C combination study (PMID:24346133)
- EPA omega-3 + Zink combination study (PMID:23644932)
- EPA omega-3 + Zink combination study (PMID:27113121)
- EPA omega-3 + Zink combination study (PMID:35587877)
- PubChem Compound 446284
Frequently Asked Questions
What is EPA (Omega-3) used for?
EPA (eicosapentaenoic acid) is an omega-3 fatty acid involved in producing eicosanoids — signaling molecules with anti-inflammatory properties.
What is the recommended dosage for EPA (Omega-3)?
1200 mg. With meal. Take with food.
Does EPA (Omega-3) interact with other supplements?
EPA (Omega-3) has 10 verified interactions. Top: Schwarzkümmelöl (Nigella sativa), Boswellia (Weihrauch).
When is the best time to take EPA (Omega-3)?
With meal. Take with food.
Is EPA (Omega-3) safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
Check how EPA (Omega-3) fits your full stack
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Check Your Stack →Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.