Garlic
Overview
Garlic (Allium sativum) contains allicin (C6H10OS2) as primary bioactive, with additional compounds including diallyl sulfides and S-allylcysteine (SAC). Reviews confirm antiproliferative, antioxidant, and anti-inflammatory effects. Clinical evidence supports modest blood pressure and lipid reduction. Allicin is unstable in supplements — aged garlic extract (AGE) provides stable SAC. Additive antiplatelet effect with anticoagulants; discontinue before surgery. May reduce saquinavir levels via CYP3A4/P-gp. Generally well tolerated; GI side effects common.
Dosage
600 mg · Any time · Can take on empty stomach
Key Interactions
22 verified interactions found
Knoblauch und Selen können in ihrer kombinierten chemoprotektiven Wirkung interagieren. Die biochemische Signifikanz ist kontextuell und dosisabhängig.
Knoblauch und Selen können in ihrer antiproliferativen Wirkung interagieren. Standarddosen (Selen ≤200mcg, Knoblauchextrakt ≤1200mg) sind unbedenklich; nicht gleichzeitig in Hochdosen kombinieren.
View details →Lycopene works synergistically with garlic to prevent the oxidation of harmful LDL cholesterol.
Knoblauch und Lycopen zeigen synergistische antioxidative Wirkungen gegen LDL-Oxidation. Kombination in Standarddosen ist unkritisch und kann sinnvoll sein.
View details →Both arginine and garlic enhance platelet nitric oxide production via distinct mechanisms.
Arginin und Knoblauch können gemeinsam die Stickstoffoxid-Produktion (NO) in Blutgefäßen unterstützen. Eine Kombination beider Supplemente gilt als sicher.
View details →CoQ10 and garlic both enhance reaction time and motor performance in the body.
Knoblauch und CoQ10 zeigen ähnliche kognitive Effekte in Studien; eine gegenseitige Beeinflussung in üblichen Dosierungen ist gering. Eine gleichzeitige Einnahme gilt als unbedenklich.
View details →Garlic supplementation increases free alanine levels significantly in muscle.
Knoblauch kann den freien Aminosäurespiegel, einschließlich L-Alanin, im Muskelgewebe beeinflussen; die Evidenz basiert auf Tierstudien. Eine klinisch relevante Interaktion beim Menschen ist nicht zu erwarten.
View details →Scientific Sources
- Source
- Source
- A historical perspective on garlic and cancer. (2001)
- Distribution, accumulation and speciation of selenium at the different growth st (2021)
- [Study on trace elements in epithelial cells during oral carcinogenesis prevente (2000)
- Efficacy of cancer prevention by high-selenium garlic is primarily dependent on (1995)
- Enrichment of selenium in allium vegetables for cancer prevention. (1994)
- Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, g (2000)
- Synergistic Effects of Food Ingredients and Vegetable Oils on Thermal Isomerizat (2020)
- Functional foods and their role in cancer prevention and health promotion: a com (2017)
- High-dose folate may improve platelet function in acute coronary syndrome and ot (2007)
- L-arginine augments the antioxidant effect of garlic against acetic acid-induced (2009)
- The subtle central effect of nutraceuticals: Is it placebo or nocebo? (2015)
- Effects of Dietary Garlic Extracts on Whole Body Amino Acid and Fatty Acid Compo (2012)
- NIH Dietary Supplement Label Database (DSLD)
Frequently Asked Questions
What is Garlic used for?
Garlic (Allium sativum) contains allicin (C6H10OS2) as primary bioactive, with additional compounds including diallyl sulfides and S-allylcysteine (SAC).
What is the recommended dosage for Garlic?
600 mg. Any time. Can take on empty stomach.
Does Garlic interact with other supplements?
Garlic has 22 verified interactions. Top: Selen, Lycopene.
When is the best time to take Garlic?
Any time. Can take on empty stomach.
Is Garlic safe to combine with other supplements?
Always check interactions before combining supplements. Use VitalStack to verify your full stack for free.
Check how Garlic fits your full stack
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Check Your Stack →Not medical advice. VitalStack is not a medical device. For personalized health recommendations, consult a healthcare provider.